Initial Public Offerings IPO News (beta) Recent Filings IPO Calendar Recent Pricings IPO Withdrawals Quiet Period Deal Flow Lockup Expirations Best-Worst Performers Industry Analysis Underwriter Performance Quarterly Reviews Secondary Offerings Recent Filings Calendar Recent Pricings Quiet Period Deal Flow Best-Worst Performers Industry Analysis Underwriter Performance Quarterly Reviews Tools Search Recent Events Underwriters Aftermarket Report	Secondary Best-Worst Performance - 2022 Year-to-Date Report 5 Best Performers Date Company Symbol % Chg. 2022-07-01 Verrica Pharmaceuticals Inc. VRCA +189.5% 2022-01-27 Sierra Oncology, Inc. SRRA +101.9% 2022-06-24 Applied Therapeutics Inc. APLT +72.0% 2022-02-24 Dogness (International) Corp DOGZ +60.8% 2022-05-25 Evelo Biosciences, Inc. EVLO +55.5% 5 Worst Performers Date Company Symbol % Chg. 2022-04-11 Stealth BioTherapeutics Corp MITO -62.9% 2022-02-15 Enveric Biosciences, Inc. ENVB -60.0% 2022-01-28 Epizyme, Inc. EPZM -58.7% 2022-03-11 U.S. Well Services, Inc. USWS -54.5% 2022-02-03 Titan Pharmaceuticals Inc. TTNP -53.4% Secondary Best-Worst Report: Percentage Change Secondary Best-Worst Report: Market Value

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